Dr Raquel Díaz Simón

Internal Medicine

Dr Raquel Díaz Simón

Specialist in
  • Women’s holistic health, vascular and cardiometabolic risk.
  • Venous thromboembolic disease and ophthalmic vascular disease.
  • Antiphospholipid syndrome, obesity, diabetes and dyslipidaemia.
«I see internal medicine as taking a holistic view of the individual: combining scientific rigour and research with listening to and providing close support for each patient.»
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Professional profile

A specialist in Internal Medicine with over thirty years’ experience and a career that combines clinical excellence, research and public outreach in women’s health. She holds a Doctor of Medicine degree from the Complutense University of Madrid and has built a leading career in comprehensive women’s healthcare, cardiometabolic risk, venous thromboembolic disease, ophthalmic vascular disease and antiphospholipid syndrome.

Her approach to Internal Medicine takes a holistic view of the individual, based on scientific rigour, active listening and close support. She combines her clinical and research work with university teaching and public outreach on women’s health, particularly in the field of the menopause and its vascular and metabolic implications.

Education

Specialist medical training in Internal Medicine, supplemented by doctoral training, advanced clinical ultrasound, systemic autoimmune diseases, good clinical practice, medical statistics and research methodology.

2024 | Doctor of Medicine, Research Programme in Medical and Surgical Sciences. Summa cum laude. Complutense University of Madrid.
2017 | Essential Good Clinical Practice. Faculty of Pharmaceutical Medicine, Royal Colleges of Physicians.
2015–2016 | Advanced Clinical Ultrasound Course. Complutense University of Madrid.
2014–2015 | University Course on Systemic Autoimmune Diseases: Diagnosis and Treatment.
2000 – 2002 | University Expert in Probability and Statistics in Medicine. National University of Distance Education. Postgraduate Diploma in Fundamentals of Design and Statistics. Autonomous University of Barcelona.
1997 | Specialist in Internal Medicine following a residency programme. 12 de Octubre University Hospital, Madrid.
1992 | Bachelor’s Degree in Medicine and Surgery. Complutense University of Madrid.

Professional experience

Clinical work carried out in hospital-based internal medicine, Emergency Department, and specialist clinics for venous thromboembolism, ophthalmic vascular disease, antiphospholipid syndrome and women’s health.

2013 – Present | Specialist Consultant. Department of Internal Medicine. 12 de Octubre University Hospital, Madrid.
2008 – 2013 | Specialist in Internal Medicine. Nuestra Señora del Rosario Clinic, Madrid.
1999 – 2008 | Specialist Doctor. Emergency Department Department. 12 de Octubre University Hospital, Madrid.

Scientific publications

Research focusing on venous thromboembolism, primary antiphospholipid syndrome, the prothrombotic state associated with COVID-19, multicentre clinical registries and vascular health. Among his most recent scientific publications are:

2025 | Cabrera-Marante O, Pleguezuelo D, Garcinuño S, Díaz-Simón R, et al. Criteria and non-criteria anti-phospholipid antibodies in the different clinical forms of antiphospholipid syndrome. Front Immunol. 2025;16:1636171. doi:10.3389/fimmu.2025.1636171
2024 | Garcinuño S, Lalueza A, Gil-Etayo FJ, Díaz-Simón R, et al. Corrigendum: Immune dysregulation is an important factor in the underlying complications of influenza infection. ApoH, IL-8 and IL-15 as prognostic markers. Front Immunol. 2024;15:1472919. doi:10.3389/fimmu.2024.1472919
2024 | Garcinuño S, Lalueza A, Gil-Etayo FJ, Díaz-Simón R, et al. Immune dysregulation is an important factor in the underlying complications of influenza infection. ApoH, IL-8 and IL-15 as markers of prognosis. Front Immunol. 2024;15:1443096. doi:10.3389/fimmu.2024.1443096
2022 | Lalueza A, Lora-Tamayo J, de la Calle C, Díaz-Simón R, et al. The utility of sepsis scores in predicting respiratory failure and death in patients with COVID-19 outside intensive care units. Rev Clin Esp. 2022;222(5):293–298. doi to be received
2021 | Pleguezuelo DE, Díaz-Simón R, et al. Case Report: Resetting the Humoral Immune Response by Targeting Plasma Cells With Daratumumab in Anti-Phospholipid Syndrome. Front Immunol. 2021;12:667515. doi:10.3389/fimmu.2021.667515

Areas of special focus

Clinical practice focusing on internal medicine, women’s health, vascular risk, thromboembolic disease, ophthalmic vascular disease and cardiometabolic disorders.

  • Venous thromboembolic disease, thrombophilias and antiphospholipid syndrome.
  • Ophthalmic vascular disease.
  • Menopause and perimenopause: a comprehensive approach to associated symptoms and risks.
  • Women’s vascular and metabolic health.
  • Obesity, insulin resistance and diabetes.
  • Bone and muscle health.

Techniques and procedures

Application of clinical procedures specific to Internal Medicine, focusing on comprehensive assessment, vascular prevention, cardiometabolic evaluation and the follow-up of patients with complex conditions.

  • Comprehensive assessment of women in perimenopause and menopause.
  • Assessment of vascular and cardiometabolic risk.
  • Diagnosis and management of venous thromboembolism.
  • Investigation of thrombophilia and antiphospholipid syndrome.
  • Clinical assessment of ophthalmic vascular disease.
  • Monitoring of obesity, insulin resistance, diabetes and dyslipidaemia.

Accreditations and memberships

It maintains active links with scientific and professional societies in the field of Internal Medicine, including:

  • Spanish Society of Internal Medicine (SEMI).
  • Madrid-Castile-La Mancha Society of Internal Medicine (SOMIMACA).

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