Metabolic Center

Autoimmune and Inflammatory Pathology Unit

The unit

Diagnostic accuracy. Personalised treatment strategy.

The Autoimmune and Inflammatory Pathology Unit offers specialist care for the diagnosis and management of immune-mediated digestive disorders that require clinical expertise and a careful assessment of intestinal inflammation, with expert judgement and follow-up tailored to each stage of the disease.

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Dr Malena García Arredondo
Head of the unit

Dr Malena García Arredondo

Specialist in
  • Disorders of the gut-brain axis (Irritable bowel syndrome and functional dyspepsia).
  • Intestinal dysbiosis and alterations in intestinal permeability.
  • Gastro-oesophageal reflux disease.
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Medical team

Our specialists

Dr Marta Barceló López

Dr Marta Barceló López

Specialist in
  • Gastro-oesophageal reflux disease and its complications.

  • Eosinophilic oesophagitis.

  • Diagnostic and therapeutic endoscopy.

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Dr Marta Cruz Aparicio

Dr Marta Cruz Aparicio

Specialist in
  • Hepatobiliary and pancreatic pathology.
  • Endoscopic staging of gastric, colorectal and pancreatic cancer.
  • Diagnostic endoscopic ultrasound and fine-needle aspiration of pancreatic lesions
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Esther Jhen Segorbe Matía

Esther Jhen Segorbe Matía

Specialist in
  • Clinical gastrointestinal nutrition and the microbiota.
  • Irritable bowel syndrome and dysbiosis.
  • Functional nutrition and metabolic regulation.
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Patient information

Autoimmune and Inflammatory Pathology Unit

Specialist diagnosis and treatment of autoimmune gastrointestinal disorders

The Autoimmune and Inflammatory Diseases Unit, part of the Gastroenterology Department at the Publio Cordón Memorial Hospital and headed by Dr Malena García Arredondo, offers specialist medical care for the diagnosis and treatment of immune-mediated digestive diseases requiring clinical expertise, expert monitoring and well-founded therapeutic decisions.

When is a specialist assessment recommended? Autoimmune digestive diseases are characterised by chronic inflammation and a variable course, with a risk of complications if they are not properly identified and treated. An expert assessment makes it possible to distinguish between actual disease activity and to determine the appropriate clinical timing for intervention.

Specialist care for patients with chronic inflammatory diseases

The unit primarily treats adult patients, providing initial consultations, ongoing follow-up and second opinions. Its work focuses on conditions that are chronic or have a complex course, requiring accurate assessment, continuity of care and a correct understanding of each stage of the disease.

The clinical aim is to support the patient from the initial diagnosis through to the most advanced therapeutic decisions, prioritising safety, appropriate treatment and the preservation of quality of life.

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Which conditions require specialist care

The unit treats a wide range of autoimmune and inflammatory digestive disorders that share complex immunological mechanisms and have a significant impact on daily life. Their management requires specific expertise and an individualised assessment.

These include, amongst others:

  • Inflammatory bowel disease: Crohn’s disease, ulcerative colitis and indeterminate colitis

  • Eosinophilic oesophagitis

  • Coeliac disease

  • Autoimmune enteritis

  • Microscopic colitis

All these conditions require structured clinical management to assess inflammatory activity, prevent complications and safely adjust treatment over time.

Looking deeper to understand complex diseases.
Looking deeper to understand complex diseases.

How inflammatory activity is assessed and treatment is decided

Care begins with a comprehensive initial consultation, based on a detailed clinical assessment and actively listening to the patient’s symptoms and concerns. Diagnostic investigations rely on advanced gastrointestinal endoscopy with biopsy sampling, imaging tests such as magnetic resonance imaging (MRI) or computed tomography (CT), specific laboratory tests and biomarkers, as well as functional tests where indicated.

All clinical and diagnostic information is rigorously integrated to determine, using expert judgement, the most appropriate treatment in each situation. Decisions are explained clearly, allowing sufficient time for patients to understand the various options and make an informed choice.

Medical treatment and advanced therapies

Treatment is tailored to each individual patient, depending on the type of disease, its inflammatory activity and the patient’s clinical condition. The unit employs a stepwise approach to medical treatment, including anti-inflammatory drugs, immunomodulators and advanced therapies where indicated, all selected on the basis of expert judgement and reviewed on a regular basis.

In specific situations, the approach is complemented by targeted nutritional interventions and specific endoscopic procedures, always integrated within a comprehensive treatment plan.

Follow-up is carried out through structured check-ups that enable the clinical and laboratory response to be assessed, treatment to be adjusted safely and potential complications to be anticipated, ensuring continuous monitoring and consistent medical care over time.

When to start, adjust or change treatment The management of these conditions requires clinical judgement when prescribing, adjusting or modifying treatment in accordance with inflammatory activity and clinical response. Correct therapeutic management is key to improving disease control and ensuring long-term safety.

Multidisciplinary coordination and support

The unit has a medical team with experience in autoimmune and inflammatory gastrointestinal conditions, accustomed to managing complex cases and making challenging clinical decisions.

Where the situation requires it, the approach is coordinated with other gastroenterology units and with specialists from different areas of the hospital, ensuring consistent multidisciplinary care.

The care model at the Publio Cordón Memorial Hospital is based on clinical humanism, ongoing support and taking the time needed to inform, assess and decide, offering each patient rigorous and personalised medical care in a trusting environment.

Specialist assessment of autoimmune and inflammatory conditions

Where an inflammatory or autoimmune disease is suspected or diagnosed, the Unit provides an expert assessment to confirm the diagnosis, tailor the necessary investigations and determine the most appropriate treatment strategy for each individual case.

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