Neuromuscular Disorders and Dysautonomia Studies Unit

The Neuromuscular and Dysautonomia Unit treats patients with muscle weakness, persistent fatigue, gait disturbances or symptoms consistent with autonomic nervous system dysfunction who require an expert neurological assessment. It intervenes from the very first clinical signs to establish an accurate diagnosis and draw up a treatment plan tailored to the progression of each individual case.

Neurological assessment in cases of progressive weakness and persistent fatigue

The unit is aimed at people with suspected or diagnosed conditions affecting the peripheral nerves, the neuromuscular junction or the muscles. Among the most common conditions are myasthenia gravis, polyneuropathies, hereditary or inflammatory myopathies, and amyotrophic lateral sclerosis (ALS).

A specialist assessment is particularly recommended in cases of progressive weakness, loss of strength, disproportionate fatigue or symptoms that cannot be explained by initial investigations. The aim is to identify the cause of the problem at an early stage and avoid delays in diagnosis.

Comprehensive study of neuromuscular disorders and disorders of the autonomic nervous system

A key feature of the unit is its Dysautonomia Laboratory, which is dedicated to the study of disorders of the autonomic nervous system – the system responsible for controlling functions such as blood pressure, heart rate and sweat regulation.

This laboratory enables specific tests to be carried out that assess autonomic function objectively and accurately. Its role is particularly important in patients with persistent symptoms following COVID-19 infection, as well as in people with chronic fatigue syndrome or fibromyalgia where an autonomic component is suspected.

The integration of neuromuscular and autonomic assessment enables us to address complex clinical presentations that require a comprehensive and specialised approach.

Differential diagnosis using advanced electromyography and genetic testing

The diagnostic process includes high-resolution electromyography, nerve conduction studies, genetic testing, biomarker analysis and advanced neuroimaging techniques where indicated.

This combination of tools enables us to accurately determine the cause of the disorder and distinguish between inflammatory, hereditary, degenerative or autoimmune processes. Complex cases are assessed in joint consultations with geneticists, pulmonologists and other relevant specialists.

Every treatment decision is based on objective clinical data and the patient’s individual clinical course, avoiding standardised approaches in conditions that require diagnostic precision.

Individualised neuromuscular treatment

Treatment is tailored to the type of disease and its stage of progression. It may include immunomodulatory therapies, intravenous immunoglobulin administration, specific symptomatic treatment and targeted neuromuscular rehabilitation programmes, always in accordance with individualised clinical criteria.

In more complex cases, such as amyotrophic lateral sclerosis (ALS), a coordinated care model is implemented, bringing together neurology, respiratory medicine, physiotherapy, speech and language therapy, and psychological support. This coordination enables us to anticipate complications, plan interventions progressively and maintain functional stability for as long as possible.

Beyond the technical aspects of treatment, the care process includes consultations dedicated to clearly explaining the expected progression of the disease, the options available at each stage and any future decisions that may be necessary. The team sets aside the necessary time to address any queries, facilitate the active involvement of the patient and their family and friends, and offer ongoing support during times of particular uncertainty.

The aim is not merely to treat the disease, but to preserve independence, maintain quality of life and provide clinical reassurance throughout the entire process.

Planned clinical follow-up and ongoing support

The care model combines a high level of diagnostic specialisation with personalised, long-term care. From the very first consultation, a follow-up plan is drawn up, tailored to the patient’s clinical progress, with regular check-ups and coordination between specialists where the condition requires it.

Clear information, forward planning and the team’s accessibility are an essential part of the care process, particularly for conditions with a chronic or progressive course. We take the time needed to explain each stage of the condition, review treatment options and address any concerns calmly.